- The Natural Hydrocortisone (NHC), even at a high dose, was no longer preventing the bleeds;
- The NHC was causing gastrointestinal bleeding (at all doses);
- The bleeds were getting worse.
- Pinuki was anemic.
- Pinuki needed a third blood transfusion.
- The surgery "solves the epistaxis in most cases of intermittent epistaxis of unknown origin." http://books.google.co.in/books?id=6fO5tHfCX10C&pg=PA79&lpg=PA79&dq=management+of+intermittent+epistaxis+of+unknown+origin&source=bl&ots=jAnLQQokxa&sig=O2JP36h49Ol4go-V6CpxKF3g-ho&hl=en&ei=HRnMTt2nN-Hb0QH84rQN&sa=X&oi=book_result&ct=result&resnum=1&ved=0CCYQ6AEwAA#v=onepage&q=management%20of%20intermittent%20epistaxis%20of%20unknown%20origin&f=false
- At some point, Pinuki will develop enough of an immune response to transfusions that there will be no useable blood available to her. She has had four blood transfusions already.
- We cannot "bank" her blood because of the anemia and even if we could, it would have a self life of 42 days.
- She is able to clot and produce new healthy red blood cells.
- Even after nine months, but for the epistaxis and anemia (secondary to the epistaxis), Pinuki's overall health has remained good. Pinuki has no other signs of illness. To see videos of Pinuki, before the surgery: https://picasaweb.google.com/102756076755266210672/PinukiBeforeRhinotomy?authkey=Gv1sRgCL7NpdaG_JCj7gE
- I could not euthanize her looking and acting as she is.
- No other viable treatments were suggested.
A lot can change in five days. Nuki is getting stronger each day and appears to be healing nicely. Her appetite is returning. Her stools are less dark. She has not had a nosebleed. Please keep her in your thoughts and prayers. This has been such a long journey so I struggle to remain even cautiously optimistic this will work.